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Histamine 2HCl (56-92-8) is a small-molecule agonist targeting histamine H1 and H2 receptors It is designed to selectively stimulate these receptors thereby modulating downstream intracellular signaling pathways Histamine 2HCl exerts its biological activity primarily through receptor agonism triggering pathways involved in neurotransmission gastric acid secretion vascular permeability and inflammation In receptor binding assays and cell-based experiments Histamine 2HCl demonstrates receptor stimulation with reported IC50 values for H1 and H2 receptor activation typically ranging from micromolar to sub-micromolar concentrations Based on these pharmacological properties Histamine 2HCl holds research potential in studies of allergic reactions gastrointestinal physiology and central nervous system functions
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Avantor Prevail HPLC columns exhibit long column lifetime in both highly aqueous and highly organic mobile phases. Avantor Prevail HPLC columns are silica based except for Prevail Carbohydrate ES. The stability of these phases is such that a single column can be switched between highly aqueous for analysis of highly polar analytes and highly organic for strong retention of hydrophobic analytes. Avantor Prevail HPLC columns are stable from highly organic to highly aqueous. Avantor Prevail HPLC columns are specialty phases for specific applications. Avantor Prevail HPLC columns provide excellent sensitivity with microbore and ELSD applications.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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